UB-EV-52
General
Type : Adamantyl,Urea derivative
Chemical_Nomenclature : 4-[4-(2-oxatricyclo[3.3.1.13,7]decan-1-ylcarbamoylamino)cyclohexyl]oxybenzoic acid
Canonical SMILES : C1CC(CCC1NC(=O)NC23CC4CC(C2)CC(C4)O3)OC5=CC=C(C=C5)C(=O)O
InChI : InChI=1S\/C23H30N2O5\/c26-21(27)16-1-5-18(6-2-16)29-19-7-3-17(4-8-19)24-22(28)25-23-12-14-9-15(13-23)11-20(10-14)30-23\/h1-2,5-6,14-15,17,19-20H,3-4,7-13H2,(H,26,27)(H2,24,25,28)
InChIKey : TUSNDHHKQPKMJV-UHFFFAOYSA-N
Other name(s) : SCHEMBL18424948,SCHEMBL18424949
MW : 414.5
Formula : C23H30N2O5
CAS_number :
PubChem : 126508342
UniChem : TUSNDHHKQPKMJV-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : UB-EV-52 ligand of proteins in family: Epoxide_hydrolase
Stucture :
Protein : human-EPHX2
References (2)
| Title : Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease - Grinan-Ferre_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Grinan-Ferre C , Companys-Alemany J , Jarne-Ferrer J , Codony S , Gonzalez-Castillo C , Ortuno-Sahagun D , Vilageliu L , Grinberg D , Vazquez S , Pallas M |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : Grinan-Ferre_2021_Int.J.Mol.Sci_22_ |
| ESTHER : Grinan-Ferre_2021_Int.J.Mol.Sci_22_ |
| PubMedSearch : Grinan-Ferre_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 33810307 |
| Title : Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease - Grinan-Ferre_2020_Neurotherapeutics__ |
| Author(s) : Grinan-Ferre C , Codony S , Pujol E , Yang J , Leiva R , Escolano C , Puigoriol-Illamola D , Companys-Alemany J , Corpas R , Sanfeliu C , Perez B , Loza MI , Brea J , Morisseau C , Hammock BD , Vazquez S , Pallas M , Galdeano C |
| Ref : Neurotherapeutics , : , 2020 |
| Abstract : Grinan-Ferre_2020_Neurotherapeutics__ |
| ESTHER : Grinan-Ferre_2020_Neurotherapeutics__ |
| PubMedSearch : Grinan-Ferre_2020_Neurotherapeutics__ |
| PubMedID: 32488482 |