Inhibitor

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Inhibitor Report for: VG

Amiton, was described in a 1955 paper by R Ghosh and J. F. Newman, as being particularly effective against mites It was brought to market as an insecticide by the company in 1954 but was subsequently withdrawn as too toxic. called phospholine in Clinton & Dettbarn but it is not echotiophate. produces a myopathy


General
Type Chemical Warfare Agent, Organophosphate, Nerve Agent V-series
Chemical_Nomenclature 2-diethoxyphosphorylsulfanyl-N,N-diethylethanamine
Canonical SMILES CCN(CC)CCSP(=O)(OCC)OCC
InChI InChI=1S/C10H24NO3PS/c1-5-11(6-2)9-10-16-15(12,13-7-3)14-8-4/h5-10H2,1-4H3
InChIKey PJISLFCKHOHLLP-UHFFFAOYSA-N
Other name(s) Metramac ; AMITON ; Inferno ; Metram ; Tetram ; Amiton [BSI] ; DSDP ; Chipman 6200 ; Caswell No. 333D ; Rhodia-6200 ; Diethyl S-2-diethylaminoethyl phosphorothioate
________________________________________________________________________________________________
MW|269.34
Formula|C10H24NO3PS
CAS_number|78-53-5
PubChem|6542
UniChem|PJISLFCKHOHLLP-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | VG ligand of proteins in family: ACHE, BCHE

References:
Search PubMed for references concerning: VG

3 more
    Title: Gas chromatographic-mass spectrometric characterisation of amiton and the recovery of amiton from concrete, paint, rubber and soil matrices
    Borrett VT, Gan TH, Lakeland BR, Leslie DR, Mathews RJ, Mattsson ER, Riddell S, Tantaro V
    Ref: Journal of Chromatography A, 1003:143, 2003 : PubMed

            

    Title: In vivo modulation of the number of muscarinic receptors in rat brain by cholinergic ligands
    Ben-Barak J, Gazit H, Silman I, Dudai Y
    Ref: European Journal of Pharmacology, 74:73, 1981 : PubMed

            

    Title: Trialkyl phosphate and phosphorothiolate anti-cholinesterases. 1. Amiton analogs
    Bracha P, O'Brien RD
    Ref: Biochemistry, 7:1545, 1968 : PubMed