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Inhibitor Report for: alkyne-PEG-FP

Non specific serine hydrolases (SH) probe. Contains a clickable alkyne tag, it is possible to conjugate with a reporter group (i.e. biotin azide or rhodamine azide) using click chemistry


General
Type Organophosphate, ABPP-Probe, Fluorescent Probe, Alkyne
Chemical_Nomenclature 5-[2-[2-[2-[2-[ethoxy(fluoro)phosphoryl]ethoxy]ethoxy]ethoxy]ethoxy]pent-1-yne
Canonical SMILES CCOP(=O)(CCOCCOCCOCCOCCCC#C)F
InChI InChI=1S/C15H28FO6P/c1-3-5-6-7-18-8-9-19-10-11-20-12-13-21-14-15-23(16,17)22-4-2/h1H,4-15H2,2H3
InChIKey UVPAJAAPPUVBDC-UHFFFAOYSA-N
Other name(s) SCHEMBL20832336
________________________________________________________________________________________________
MW|354.35
Formula|C15H28FO6P
CAS_number|
PubChem|138484657
UniChem|UVPAJAAPPUVBDC-UHFFFAOYSA-N
IUPHAR|
Wikipedia|


References:
Search PubMed for references concerning: alkyne-PEG-FP
    Title: Small-Molecule Probes Reveal Esterases with Persistent Activity in Dormant and Reactivating Mycobacterium tuberculosis
    Tallman KR, Levine SR, Beatty KE
    Ref: ACS Infect Dis, 2:936, 2016 : PubMed

            

    Title: Multiplexed activity-based protein profiling of the human pathogen Aspergillus fumigatus reveals large functional changes upon exposure to human serum
    Wiedner SD, Burnum KE, Pederson LM, Anderson LN, Fortuin S, Chauvigne-Hines LM, Shukla AK, Ansong C, Panisko EA and Wright AT <1 more author(s)>
    Ref: Journal of Biological Chemistry, 287:33447, 2012 : PubMed