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Inhibitor Report for: dMgerminone

IC50 (nM)with YLG as substrate: rac-GR24, AT14 32.9 +/- 6.0; Germinone AT14 12.2 +/- 10; KAI2 585 +/- 36; dMgerminone AT14 162 +/- 9.0; KAI2 46.4 +/- 3.0


General
Type Strigolactone, Debranone, Strigolactone receptors ligand
Chemical_Nomenclature 5-(4-Phenyl-2-nitrophenoxy)-furan-2(5H)-one
Canonical SMILES C1(=C(C=CC(=C1)C2=CC=CC=C2)OC3C=CC(O3)=O)[N+](=O)[O-]
InChI InChI=1S/C16H11NO5/c18-15-8-9-16(22-15)21-14-7-6-12(10-13(14)17(19)20)11-4-2-1-3-5-11/h1-10,16H
InChIKey XJPYTXLINPRYAJ-UHFFFAOYSA-N
Other name(s) desmethyl-type germinone ; dMGer
________________________________________________________________________________________________
MW|297.26
Formula|C16H11NO5
CAS_number|
PubChem|
UniChem|XJPYTXLINPRYAJ-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Protein | arath-AtD14, arath-KAI2.D14L

References:
Search PubMed for references concerning: dMgerminone
    Title: Desmethyl type germinone, a specific agonist for the HTL/KAI2 receptor, induces the Arabidopsis seed germination in a gibberellin-independent manner
    Okabe S, Kitaoka K, Suzuki T, Kuruma M, Hagihara S, Yamaguchi S, Fukui K, Seto Y
    Ref: Biochemical & Biophysical Research Communications, 649:110, 2023 : PubMed