Mutation

Kinetic parameters

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Kinetic parameters for mutation L286K_human-BCHE

Substrate

MoleculeKmKcatExp. conditionsReference
Butyrylthiocholine 22 mM - 100mM Na phosphate pH7.4 T22C Gnatt_1994_J.Neurochem_62_749

Inhibitor

MoleculeKiKsiIc50Exp. conditionsSubstrateReference
Echothiophate - - >1000 uM 100mM Na phosphate pH7.4 T22C Butyrylthiocholine Gnatt_1994_J.Neurochem_62_749
Iso-OMPA - - 100 uM 100mM Na phosphate pH7.4 T22C Butyrylthiocholine Gnatt_1994_J.Neurochem_62_749

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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