Mutation
Kinetic parameters
Tree Display
AceDB Schema
XML Display
Feedback

Kinetic parameters for mutation Y72N/Y124Q_mouse-ACHE

Substrate

MoleculeKmKcatExp. conditionsReference
Acetylthiocholine 95 & 11 uM 94000 & 20000/min 100mM NaP pH7 T22C eq3 sch3 Radic_1993_Biochemistry_32_12074

Inhibitor

MoleculeKiKsiIc50Exp. conditionsSubstrateReference
BW284C51 190 & 80 nM 460 & 130 nM - 100mM NaP pH7.0 T22C eq3.gif sch3.gif Acetylthiocholine Radic_1993_Biochemistry_32_12074
Decamethonium 130 & 14 uM 510 & 180 uM - 100mM NaP pH7.0 T22C eq3.gif sch3.gif Acetylthiocholine Radic_1993_Biochemistry_32_12074
Propidium 35 & 7 uM 120 & 44 uM - 100mM NaP pH7.0 T22C eq3.gif sch3.gif Acetylthiocholine Radic_1993_Biochemistry_32_12074
WT-fasciculin2 - 95 & 10 nM - 100mM NaP pH7.0 T37C eq4 sch4 meth6 Acetylthiocholine Radic_1994_J.Biol.Chem_269_11233
Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer