Mutation

Kinetic parameters

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Kinetic parameters for mutation Y72N_human-ACHE

Substrate

MoleculeKmKcatExp. conditionsReference
Acetylthiocholine 140 mM 5.4 10+5/min IS 50mM phosphate pH8 T27C Kaplan_2001_Biochemistry_40_7433
Butyrylthiocholine 0.14 mM 0.09 10+5/min IS 50mM phosphate pH8 T27C Kaplan_2001_Biochemistry_40_7433

Inhibitor

MoleculeKiKsiIc50Exp. conditionsSubstrateReference

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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