Gene Locus : human-CES1
Mode of mutation : Natural mutant
Disease :
Summary : Natural mutant Wang_2017_Drug.Metab.Dispos_45_1149
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Natural mutation
Torpedo_number : 249
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.Ala269Ser Nucleotide change G913T rs115629050
| Title : A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms - Wang_2017_Drug.Metab.Dispos_45_1149 |
| Author(s) : Wang X , Rida N , Shi J , Wu AH , Bleske BE , Zhu HJ |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 45 :1149 , 2017 |
| Abstract : Wang_2017_Drug.Metab.Dispos_45_1149 |
| ESTHER : Wang_2017_Drug.Metab.Dispos_45_1149 |
| PubMedSearch : Wang_2017_Drug.Metab.Dispos_45_1149 |
| PubMedID: 28838926 |
| Gene_locus related to this paper: human-CES1 |
| Title : Population Pharmacokinetics of Methylphenidate in Healthy Adults Emphasizing Novel and Known Effects of Several Carboxylesterase 1 (CES1) Variants - Lyauk_2016_Clin.Transl.Sci_9_337 |
| Author(s) : Lyauk YK , Stage C , Bergmann TK , Ferrero-Milliani L , Bjerre D , Thomsen R , Dalhoff KP , Rasmussen HB , Jurgens G |
| Ref : Clin Transl Sci , 9 :337 , 2016 |
| Abstract : Lyauk_2016_Clin.Transl.Sci_9_337 |
| ESTHER : Lyauk_2016_Clin.Transl.Sci_9_337 |
| PubMedSearch : Lyauk_2016_Clin.Transl.Sci_9_337 |
| PubMedID: 27754602 |
| Gene_locus related to this paper: human-CES1 |