Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Substrate activation substrate activation Masson_2001_Biochim.Biophys.Acta_1544_166 || Aging A328G decreases half-life of aging by DFP 0.9 times Masson_1997_Biochem.J_327_601
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Substrate activation
Torpedo_number : 330
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.A328G Ala328Gly (p.A356G Ala356Gly in primary sequence with 28 amino-acids signal peptide) decreases half-life of aging by DFP 0.9 times
| Title : Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase - Masson_2001_Biochim.Biophys.Acta_1544_166 |
| Author(s) : Masson P , Xie W , Froment MT , Lockridge O |
| Ref : Biochimica & Biophysica Acta , 1544 :166 , 2001 |
| Abstract : Masson_2001_Biochim.Biophys.Acta_1544_166 |
| ESTHER : Masson_2001_Biochim.Biophys.Acta_1544_166 |
| PubMedSearch : Masson_2001_Biochim.Biophys.Acta_1544_166 |
| PubMedID: 11341926 |
| Gene_locus related to this paper: human-BCHE |
| Title : Aging of di-isopropyl-phosphorylated human butyrylcholinesterase - Masson_1997_Biochem.J_327_601 |
| Author(s) : Masson P , Fortier PL , Albaret C , Froment MT , Bartels CF , Lockridge O |
| Ref : Biochemical Journal , 327 ( Pt 2) :601 , 1997 |
| Abstract : Masson_1997_Biochem.J_327_601 |
| ESTHER : Masson_1997_Biochem.J_327_601 |
| PubMedSearch : Masson_1997_Biochem.J_327_601 |
| PubMedID: 9359435 |