Gene Locus : human-CES1
Mode of mutation : Natural mutant
Disease :
Summary :
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity : CES-1 deficiency
Modification :
Torpedo_number : No torpedo number
Kinetic Parameter : No kinetic parameter
News : No news
Comment : a genomic translocation of the 5' region from the poorly expressed pseudogene CES1P1, to CES1, yielding the structural variant CES1VAR
| Title : The impact of CES1 genotypes on the pharmacokinetics of methylphenidate in healthy Danish subjects - Stage_2017_Br.J.Clin.Pharmacol_83_1506 |
| Author(s) : Stage C , Jurgens G , Guski LS , Thomsen R , Bjerre D , Ferrero-Miliani L , Lyauk YK , Rasmussen HB , Dalhoff K |
| Ref : British Journal of Clinical Pharmacology , 83 :1506 , 2017 |
| Abstract : Stage_2017_Br.J.Clin.Pharmacol_83_1506 |
| ESTHER : Stage_2017_Br.J.Clin.Pharmacol_83_1506 |
| PubMedSearch : Stage_2017_Br.J.Clin.Pharmacol_83_1506 |
| PubMedID: 28087982 |
| Gene_locus related to this paper: human-CES1 |
| Title : Nomenclature for alleles of the human carboxylesterase 1 gene - |
| Author(s) : Rasmussen HB , Madsen MB , Hansen PR |
| Ref : Pharmacogenet Genomics , 27 :78 , 2017 |
| PubMedID: 27831961 |
| Gene_locus related to this paper: human-CES1 |
| Title : Regulatory effects of genomic translocations at the human carboxylesterase-1 (CES1) gene locus - Sanford_2016_Pharmacogenet.Genomics_26_197 |
| Author(s) : Sanford JC , Wang X , Shi J , Barrie ES , Wang D , Zhu HJ , Sadee W |
| Ref : Pharmacogenet Genomics , 26 :197 , 2016 |
| Abstract : Sanford_2016_Pharmacogenet.Genomics_26_197 |
| ESTHER : Sanford_2016_Pharmacogenet.Genomics_26_197 |
| PubMedSearch : Sanford_2016_Pharmacogenet.Genomics_26_197 |
| PubMedID: 26871237 |
| Gene_locus related to this paper: human-CES1 |
| Title : CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors - Wang_2016_Pharmacogenomics.J_16_220 |
| Author(s) : Wang X , Wang G , Shi J , Aa JY , Comas R , Liang Y , Zhu HJ |
| Ref : Pharmacogenomics J , 16 :220 , 2016 |
| Abstract : Wang_2016_Pharmacogenomics.J_16_220 |
| ESTHER : Wang_2016_Pharmacogenomics.J_16_220 |
| PubMedSearch : Wang_2016_Pharmacogenomics.J_16_220 |
| PubMedID: 26076923 |
| Gene_locus related to this paper: human-CES1 |