Kinetic parameters

Tree Display

AceDB Schema

XML Display


Mutation Report for: D74N/W286A_human-ACHE

Mode of mutation|Site directed mutagenesis
Amino Acid change|D74N/W286A
Torpedo number|72,279//279//72
Comment|p.D74N/W286A Asp74Gln/Trp286Ala (p.D105N/W317A Asp105Gln/Trp317Ala in primary sequence with 31 amino-acids signal peptide) Peripheral Anionic Site;cooperativity of mutations D74 W286 10+4 increase Ki
Kinetic parameters|none

    Title: Molecular Aspects of Catalysis and of Allosteric Regulation of Aceytlcholinesterases
    Shafferman A, Ordentlich A, Barak D, Kronman C, Ariel N, Leitner M, Segall Y, Bromberg A, Reuveny S and Velan B <4 more author(s)>
    Ref: In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases, (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp.:189, 1995 : PubMed


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

Acknowledgements and disclaimer