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Mutation Report for: G119S/A280T/F331W_tetur-ACHE

G119S/A280T/F331W_tetur-ACHE
Gene_Locus|tetur-ACHE
Mode of mutation|Natural mutant
Amino Acid change|G119S/A280T/F331W
Torpedo number|119//280//331//119,280,331
Summary|
Comment|AChE gene duplication results in the proportional overexpression which is necessary for the reduced catalytic activity caused by mutations. Triple mutant GAF->STW
Kinetic parameters|none


References:
    Title: The overexpression of acetylcholinesterase compensates for the reduced catalytic activity caused by resistance-conferring mutations in Tetranychus urticae
    Kwon DH, Choi JY, Je YH, Lee SH
    Ref: Insect Biochemistry & Molecular Biology, 42:212, 2012 : PubMed

            




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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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