Gene Locus : human-PLA2G7
Mode of mutation : Natural mutant
Disease : Suceptibility to asthma and atopy, Platelet-activating factor acetylhydrolase (PLA2G7) deficiency (PAFAD) coronary artery disease risk factor
Summary :
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification :
Torpedo_number : No torpedo number
Kinetic Parameter : No kinetic parameter
News : No news
Comment : Common polymorphism\; associated with asthma and atopy. rs1805018
| Title : Interaction between nonsynonymous polymorphisms in PLA2G7 gene and smoking on the risk of coronary heart disease in a Chinese population - Chi_2018_J.Thromb.Thrombolysis_46_125 |
| Author(s) : Chi Y , Shi C , Zhang X , Xi Y |
| Ref : J Thromb Thrombolysis , 46 :125 , 2018 |
| Abstract : Chi_2018_J.Thromb.Thrombolysis_46_125 |
| ESTHER : Chi_2018_J.Thromb.Thrombolysis_46_125 |
| PubMedSearch : Chi_2018_J.Thromb.Thrombolysis_46_125 |
| PubMedID: 29728838 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Associations between four types of single-nucleotide polymorphisms in PLA2G7 gene and clinical atherosclerosis: a meta-analysis - Santoso_2017_Am.J.Cardiovasc.Dis_7_122 |
| Author(s) : Santoso A , Maulana R , Alzahra F , Maghfirah I , Putrinarita AD , Heriansyah T |
| Ref : Am J Cardiovasc Dis , 7 :122 , 2017 |
| Abstract : Santoso_2017_Am.J.Cardiovasc.Dis_7_122 |
| ESTHER : Santoso_2017_Am.J.Cardiovasc.Dis_7_122 |
| PubMedSearch : Santoso_2017_Am.J.Cardiovasc.Dis_7_122 |
| PubMedID: 29348973 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Genetic variants and haplotypes of lipoprotein associated phospholipase A2 and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study) - Hoffmann_2009_J.Thromb.Haemost_7_41 |
| Author(s) : Hoffmann MM , Winkler K , Renner W , Winkelmann BR , Seelhorst U , Wellnitz B , Boehm BO , Marz W |
| Ref : J Thromb Haemost , 7 :41 , 2009 |
| Abstract : Hoffmann_2009_J.Thromb.Haemost_7_41 |
| ESTHER : Hoffmann_2009_J.Thromb.Haemost_7_41 |
| PubMedSearch : Hoffmann_2009_J.Thromb.Haemost_7_41 |
| PubMedID: 18983494 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Inter-individual variability of plasma PAF-acetylhydrolase activity in ARDS patients and PAFAH genotype - Li_2009_J.Clin.Pharm.Ther_34_447 |
| Author(s) : Li S , Stuart L , Zhang Y , Meduri GU , Umberger R , Yates CR |
| Ref : J Clin Pharm Ther , 34 :447 , 2009 |
| Abstract : Li_2009_J.Clin.Pharm.Ther_34_447 |
| ESTHER : Li_2009_J.Clin.Pharm.Ther_34_447 |
| PubMedSearch : Li_2009_J.Clin.Pharm.Ther_34_447 |
| PubMedID: 19583678 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets - Sutton_2008_Hum.Mol.Genet_17_1318 |
| Author(s) : Sutton BS , Crosslin DR , Shah SH , Nelson SC , Bassil A , Hale AB , Haynes C , Goldschmidt-Clermont PJ , Vance JM , Seo D , Kraus WE , Gregory SG , Hauser ER |
| Ref : Hum Mol Genet , 17 :1318 , 2008 |
| Abstract : Sutton_2008_Hum.Mol.Genet_17_1318 |
| ESTHER : Sutton_2008_Hum.Mol.Genet_17_1318 |
| PubMedSearch : Sutton_2008_Hum.Mol.Genet_17_1318 |
| PubMedID: 18204052 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension - Kokubo_2006_Hypertens.Res_29_611 |
| Author(s) : Kokubo Y , Tomoike H , Tanaka C , Banno M , Okuda T , Inamoto N , Kamide K , Kawano Y , Miyata T |
| Ref : Hypertens Res , 29 :611 , 2006 |
| Abstract : Kokubo_2006_Hypertens.Res_29_611 |
| ESTHER : Kokubo_2006_Hypertens.Res_29_611 |
| PubMedSearch : Kokubo_2006_Hypertens.Res_29_611 |
| PubMedID: 17137217 |
| Gene_locus related to this paper: human-LIPC |
| Title : The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma - Kruse_2000_Am.J.Hum.Genet_66_1522 |
| Author(s) : Kruse S , Mao XQ , Heinzmann A , Blattmann S , Roberts MH , Braun S , Gao PS , Forster J , Kuehr J , Hopkin JM , Shirakawa T , Deichmann KA |
| Ref : American Journal of Human Genetics , 66 :1522 , 2000 |
| Abstract : Kruse_2000_Am.J.Hum.Genet_66_1522 |
| ESTHER : Kruse_2000_Am.J.Hum.Genet_66_1522 |
| PubMedSearch : Kruse_2000_Am.J.Hum.Genet_66_1522 |
| PubMedID: 10733466 |
| Gene_locus related to this paper: human-PLA2G7 |
| Title : Systematic screening of the LDL-PLA2 gene for polymorphic variants and case-control analysis in schizophrenia - Bell_1997_Biochem.Biophys.Res.Commun_241_630 |
| Author(s) : Bell R , Collier DA , Rice SQ , Roberts GW , Macphee CH , Kerwin RW , Price J , Gloger IS |
| Ref : Biochemical & Biophysical Research Communications , 241 :630 , 1997 |
| Abstract : Bell_1997_Biochem.Biophys.Res.Commun_241_630 |
| ESTHER : Bell_1997_Biochem.Biophys.Res.Commun_241_630 |
| PubMedSearch : Bell_1997_Biochem.Biophys.Res.Commun_241_630 |
| PubMedID: 9434759 |
| Gene_locus related to this paper: human-PLA2G7 |