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Mutation Report for: L76S_ratno-ACHE

L76S_ratno-ACHE
Gene_Locus|ratno-ACHE
Mode of mutation|Site directed mutagenesis
Amino Acid change|L76S
Torpedo number|74
Summary|
Comment|mutation with mouse numbering (L74S in torpedo numbering) this is the reverse of S74L_eleel-ACHE which abolished inhibition by Elec-408
Kinetic parameters|none


References:
    Title: The binding sites of inhibitory monoclonal antibodies on acetylcholinesterase. Identification of a novel regulatory site at the putative back door
    Simon S, Le Goff A, Frobert Y, Grassi J, Massoulie J
    Ref: Journal of Biological Chemistry, 274:27740, 1999 : PubMed

            




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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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