Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Choline binding site Position near the choline binding site. No activity Gnatt_1994_J.Neurochem_62_749
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Choline binding site
Torpedo_number : 439
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.M437D Met437Asp (p.M465D Met465Asp in primary sequence with 28 amino-acids signal peptide) Position near the choline binding site. No activity
| Title : Site-directed mutagenesis of active site residues reveals plasticity of human butyrylcholinesterase in substrate and inhibitor interactions - Gnatt_1994_J.Neurochem_62_749 |
| Author(s) : Gnatt A , Loewenstein Y , Yaron A , Schwarz M , Soreq H |
| Ref : Journal of Neurochemistry , 62 :749 , 1994 |
| Abstract : Gnatt_1994_J.Neurochem_62_749 |
| ESTHER : Gnatt_1994_J.Neurochem_62_749 |
| PubMedSearch : Gnatt_1994_J.Neurochem_62_749 |
| PubMedID: 8294937 |