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Mutation Report for: W121A_drome-ACHE

W121A_drome-ACHE
Gene_Locus|drome-ACHE
Mode of mutation|Site directed mutagenesis
Amino Acid change|W121A
Torpedo number|84
Summary|
Comment|p.Trp121Ala
Kinetic parameters|none


References:
    Title: Conformational rigidity of cholinesterases allows for the prediction of combined effects in a particular double mutant
    Stojan J
    Ref: Chemico-Biological Interactions, 259:110, 2016 : PubMed

            

    Title: Insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge by enlarging a back channel
    Nachon F, Stojan J, Fournier D
    Ref: Febs J, 275:2659, 2008 : PubMed

            

    Title: Acetylcholinesterase engineering for detection of insecticide residues
    Boublik Y, Saint-Aguet P, Lougarre A, Arnaud M, Villatte F, Estrada-Mondaca S, Fournier D
    Ref: Protein Engineering, 15:43, 2002 : PubMed

            

    Title: Exploration of the Drosophila acetylcholinesterase substrate activation site using a reversible inhibitor (Triton X-100) and mutated enzymes
    Marcel V, Estrada-Mondaca S, Magne F, Stojan J, Klaebe A, Fournier D
    Ref: Journal of Biological Chemistry, 275:11603, 2000 : PubMed

            




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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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