Gene Locus : drome-ACHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Peripheral Anionic Site changes conformation of catalytic site Mutero_1992_Neuroreport_3_39 || Binding of Triton X-100 studies mimic the torpedo enzyme, no effect Marcel_2000_J.Biol.Chem_275_11603
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Peripheral Anionic Site || Binding of Triton X-100 studies
Torpedo_number : 72
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.Tyr109Asp
| Title : Exploration of the Drosophila acetylcholinesterase substrate activation site using a reversible inhibitor (Triton X-100) and mutated enzymes - Marcel_2000_J.Biol.Chem_275_11603 |
| Author(s) : Marcel V , Estrada-Mondaca S , Magne F , Stojan J , Klaebe A , Fournier D |
| Ref : Journal of Biological Chemistry , 275 :11603 , 2000 |
| Abstract : Marcel_2000_J.Biol.Chem_275_11603 |
| ESTHER : Marcel_2000_J.Biol.Chem_275_11603 |
| PubMedSearch : Marcel_2000_J.Biol.Chem_275_11603 |
| PubMedID: 10766776 |
| Title : Catalytic properties of cholinesterases: importance of tyrosine 109 in Drosophila protein - Mutero_1992_Neuroreport_3_39 |
| Author(s) : Mutero A , Pralavorio M , Simeon-Rudolf V , Fournier D |
| Ref : Neuroreport , 3 :39 , 1992 |
| Abstract : Mutero_1992_Neuroreport_3_39 |
| ESTHER : Mutero_1992_Neuroreport_3_39 |
| PubMedSearch : Mutero_1992_Neuroreport_3_39 |
| PubMedID: 1611033 |