DDVP-inhibited rat diaphragm AChE reactivation by oxime K027/K203 was dose-dependent.
Dose-response relationships were described by 4-parameter exponential and Hill models.
Maximum size of DDVP-inhibited AChE reactivation by K-oximes was 2.1-fold.
Oxime K027 had 5-fold higher relative reactivating potency compared to oxime K203.
        
Related information
Citations formats
Antonijevic E, Musilek K, Kuca K, Djukic-Cosic D, Andjelkovic M, Djordjevic AB, Antonijevic B (2019) Comparison of oximes K203 and K027 based on Benchmark dose analysis of rat diaphragmal acetylcholinesterase reactivation Chemico-Biological Interactions308: 385-391
Antonijevic E, Musilek K, Kuca K, Djukic-Cosic D, Andjelkovic M, Djordjevic AB, Antonijevic B (2019) Chemico-Biological Interactions308: 385-391