A spectrofluorimetric method to determine tacrine is proposed and applied to the determination of tacrine in human serum and pharmaceuticals. The fluorimetric method allows the determination of 1-70 ng ml-1 of tacrine in aqueous solutions containing acetic acid-sodium acetate buffer (pH 5.6) with lambda exc = 242 nm and lambda em = 362 nm.
        
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Aparico I, Bello MA, Callejon M, Jimenez JC, Guiraum A (1998) Spectrofluorimetric determination of tacrine in pharmaceuticals and spiked human serum Analyst123: 1575-6
Aparico I, Bello MA, Callejon M, Jimenez JC, Guiraum A (1998) Analyst123: 1575-6