Enzymes acetylcholinesterase (AChE; E.C. 3.1.1.7) and butyrylcholinesterase (BChE; E.C. 3.1.1.8) have intensively been investigated in biomedicine and toxicology due to important role in organisms. Even if structurally homologous, they differ in catalytic activity, specificity, for substrates, and selectivity in binding to many ligands. This paper compiles the results of research on cholinesterases and their interactions with ligands and inhibitors, and identifies amino acids of active sites involved in these interactions.
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Citations formats
Bosak A, Katalinic M, Kovarik Z (2011) [Cholinesterases: structure, role, and inhibition] Arh Hig Rada Toksikol62: 175-90
Bosak A, Katalinic M, Kovarik Z (2011) Arh Hig Rada Toksikol62: 175-90
