Paper Report for: Castro_2001_Mini.Rev.Med.Chem_1_267
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Title: Peripheral and dual binding site acetylcholinesterase inhibitors: implications in treatment of Alzheimer's disease Castro A, Martinez A Ref: Mini Rev Med Chem, 1:267, 2001 : PubMed
Recently advances in understanding the molecular basis of Alzheimer's disease have led to the consideration of the relationship between cholinergic inhibitors and amyloid deposition as a new hypothesis for the future rational design of effective anti-Alzheimer drugs. In the present review, the non-cholinergic functions of acetylcholinesterase (AChE) and the therapeutic potential of peripheral and dual binding site AChE inhibitors in delaying the neurodegenerative process will be discussed.
        
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Castro A, Martinez A (2001) Peripheral and dual binding site acetylcholinesterase inhibitors: implications in treatment of Alzheimer's disease Mini Rev Med Chem1: 267-72
Castro A, Martinez A (2001) Mini Rev Med Chem1: 267-72