Paper Report for: Chiaia_1995_Brain.Res.Dev.Brain.Research_84_271
Reference
Title: Neonatal infraorbital nerve transection and blockade of axoplasmic transport reduce expression of acetylcholinesterase by thalamocortical axons Chiaia NL, Rhoades RW, Bennett-Clarke CA Ref: Brain Research Developmental Brain Research, 84:271, 1995 : PubMed
Acetylcholinesterase (AChE) is transiently expressed by ventrobasal thalamic neurons and their axons in the primary somatosensory cortex and this enzyme has been used as a marker for these axons in studies concerned with cortical development and plasticity. The present experiment evaluated the effects of both peripheral nerve transection and blockade of axoplasmic transport upon the expression of AChE in thalamic axon terminals in the primary somatosensory cortex. Both manipulations resulted in marked reductions in the density of AChE in thalamocortical axons and less dramatic decreases in the density of this enzyme in thalamic neurons. These results indicate that AChE may not invariably provide unequivocal information about the distribution of somatosensory thalamocortical axon terminals in developing rodents.
        
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Chiaia NL, Rhoades RW, Bennett-Clarke CA (1995) Neonatal infraorbital nerve transection and blockade of axoplasmic transport reduce expression of acetylcholinesterase by thalamocortical axons Brain Research Developmental Brain Research84: 271-7
Chiaia NL, Rhoades RW, Bennett-Clarke CA (1995) Brain Research Developmental Brain Research84: 271-7