Paper Report for: Fleming_1996_Parasitol_113 Suppl_S175
Reference
Title: Molecular cloning and in vitro expression of C. elegans and parasitic nematode ionotropic receptors Fleming JT, Baylis HA, Sattelle DB, Lewis JA Ref: Parasitology, 113 Suppl:S175, 1996 : PubMed
The free living nematode, C. elegans is understood at a level of detail equalled by few other organisms, and much of the cell biology and sequence information is proving of considerable utility in the study of parasitic nematodes. Already, C. elegans provides a convenient vehicle for investigating anthelmintic drug action and resistance mechanisms. Among the ionotropic receptors, with their important roles in the behaviour and development of the organism, are targets for anthelmintics. The subunits of nicotinic acetylcholine receptors of C. elegans form a large and diverse multigene family. Members of this family are among the 11 genes associated with resistance to the anthelmintic drug levamisole.
        
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Fleming JT, Baylis HA, Sattelle DB, Lewis JA (1996) Molecular cloning and in vitro expression of C. elegans and parasitic nematode ionotropic receptors Parasitology113 Suppl: S175-90
Fleming JT, Baylis HA, Sattelle DB, Lewis JA (1996) Parasitology113 Suppl: S175-90