Paper Report for: Hymowitz_1978_Pharmacol.Biochem.Behav_8_203
Reference
Title: Effects of salsolinol, a tetrahydroisoquinolone alkaloid, on multiple schedule performance in rats Hymowitz N, Brezenoff HE Ref: Pharmacol Biochem Behav, 8:203, 1978 : PubMed
Rats were trained to lever press under a multiple fixed-ratio fixed-interval schedule of food reinforcement. Intracerebroventricular injections of salsolinol (1-methyl-6,7-dihydroxytetrahydroisoquinoline), a condensation product of dopamine and acetaldehyde, caused a dose-related decrease in fixed-ratio responding over a dosage range of 15-120 microgram. In contrast, fixed-interval responding was only reduced at the 120 microgram dose and was increased in two of the animals after injection of 15-30 microgram of salsolinol.
        
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Hymowitz N, Brezenoff HE (1978) Effects of salsolinol, a tetrahydroisoquinolone alkaloid, on multiple schedule performance in rats Pharmacol Biochem Behav8: 203-5
Hymowitz N, Brezenoff HE (1978) Pharmacol Biochem Behav8: 203-5