Title : Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE\/GSK3beta inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine - Jiang_2021_Eur.J.Med.Chem_223_113663 |
Author(s) : Jiang X , Liu C , Zou M , Xie H , Lin T , Lyu W , Xu J , Li Y , Feng F , Sun H , Liu W |
Ref : Eur Journal of Medicinal Chemistry , 223 :113663 , 2021 |
Abstract : Jiang_2021_Eur.J.Med.Chem_223_113663 |
ESTHER : Jiang_2021_Eur.J.Med.Chem_223_113663 |
PubMedSearch : Jiang_2021_Eur.J.Med.Chem_223_113663 |
PubMedID: 34198150 |
Jiang X, Liu C, Zou M, Xie H, Lin T, Lyu W, Xu J, Li Y, Feng F, Sun H, Liu W (2021)
Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE\/GSK3beta inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine
Eur Journal of Medicinal Chemistry
223 :113663
Jiang X, Liu C, Zou M, Xie H, Lin T, Lyu W, Xu J, Li Y, Feng F, Sun H, Liu W (2021)
Eur Journal of Medicinal Chemistry
223 :113663