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Paper Report for: Kosak_2018_J.Med.Chem_61_119

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Title: The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity
Kosak U, Brus B, Knez D, Zakelj S, Trontelj J, Pislar A, Sink R, Jukic M, Zivin M and Gobec S <8 more author(s)>
Ref: Journal of Medicinal Chemistry, 61:119, 2018 : PubMed

        



Related information

Gene_Locus| human-BCHE
Structure in RCSB-PDB | 5NN0
Structure in ESTHER | 5NN0
Inhibitor | 5NN0-cpd3,


Citations formats

Kosak U, Brus B, Knez D, Zakelj S, Trontelj J, Pislar A, Sink R, Jukic M, Zivin M, Podkowa A, Nachon F, Brazzolotto X, Stojan J, Kos J, Coquelle N, Salat K, Colletier JP, Gobec S (2018)
The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity
Journal of Medicinal Chemistry 61: 119-139

Kosak U, Brus B, Knez D, Zakelj S, Trontelj J, Pislar A, Sink R, Jukic M, Zivin M, Podkowa A, Nachon F, Brazzolotto X, Stojan J, Kos J, Coquelle N, Salat K, Colletier JP, Gobec S (2018)
Journal of Medicinal Chemistry 61: 119-139



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