Paper Report for: Nadarajah_1992_J.Anal.Toxicol_16_192
Reference
Title: The effect of pralidoxime chloride in the assay of acetylcholinesterase using 5,5'-dithio-bis(2-nitrobenzoic acid) (Ellman's reagent) Nadarajah B Ref: Journal of Analytical Toxicology, 16:192, 1992 : PubMed
Pralidoxime chloride (PAM) hydrolyzes acetylthiocholine, the substrate used in the assay of red cell cholinesterase. The thiocholine that is produced forms a yellow complex when Ellman's reagent is used in the assay. This was tested in blood samples of patients who were treated with PAM after organophosphorus (OP) poisoning and after the observation of an immediate increase in absorption of light at 412 nm.
        
Related information
Citations formats
Nadarajah B (1992) The effect of pralidoxime chloride in the assay of acetylcholinesterase using 5,5'-dithio-bis(2-nitrobenzoic acid) (Ellman's reagent) Journal of Analytical Toxicology16: 192-3
Nadarajah B (1992) Journal of Analytical Toxicology16: 192-3