Paper Report for: Passicos_2004_Biotechnol.Lett_26_1073
Reference
Title: Regioselective acylation of flavonoids catalyzed by immobilized Candida antarctica lipase under reduced pressure Passicos E, Santarelli X, Coulon D Ref: Biotechnol Lett, 26:1073, 2004 : PubMed
A single-step acylation of rutin and naringin, catalyzed by immobilized Candida antarctica lipase B in 2-methyl-2-butanol, occurred preferentially on the primary hydroxyl group. Using palmitic methyl ester as acyl donor, the acylation rate of naringin was 10-fold higher than that of rutin. Under optimal conditions, i.e. a molar ratio acyl donor/naringin of 7:1 and 200 mbar, 92% naringin was acylated.
Passicos E, Santarelli X, Coulon D (2004) Regioselective acylation of flavonoids catalyzed by immobilized Candida antarctica lipase under reduced pressure Biotechnol Lett26: 1073-6
Passicos E, Santarelli X, Coulon D (2004) Biotechnol Lett26: 1073-6