| Title : Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3 - Sanghani_2004_Drug.Metab.Dispos_32_505 |
| Author(s) : Sanghani SP , Quinney SK , Fredenburg TB , Davis WI , Murry DJ , Bosron WF |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 32 :505 , 2004 |
| Abstract : Sanghani_2004_Drug.Metab.Dispos_32_505 |
| ESTHER : Sanghani_2004_Drug.Metab.Dispos_32_505 |
| PubMedSearch : Sanghani_2004_Drug.Metab.Dispos_32_505 |
| PubMedID: 15100172 |
| Gene_locus related to this paper: human-CES2 , human-CES3 |
| Gene_locus related to this paper: human-CES2 , human-CES3 |
Sanghani SP, Quinney SK, Fredenburg TB, Davis WI, Murry DJ, Bosron WF (2004)
Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3
Drug Metabolism & Disposition: The Biological Fate of Chemicals
32 :505
Sanghani SP, Quinney SK, Fredenburg TB, Davis WI, Murry DJ, Bosron WF (2004)
Drug Metabolism & Disposition: The Biological Fate of Chemicals
32 :505