Paper Report for: Schladitz-Keil_1985_J.Chromatogr_345_99
Reference
Title: Fluorimetric determination of the quaternary compound trospium and its metabolite in biological material after derivatization with benoxaprofen chloride Schladitz-Keil G, Spahn H, Mutschler E Ref: Journal of Chromatography, 345:99, 1985 : PubMed
The quantitative determination of the quaternary compound trospium and the corresponding spiroalcohol is described for human biological material. Analysis is performed by alkaline hydrolysis, ion-pair extraction into chloroform, subsequent derivatization with the flurophor benoxaprofen chloride and high-performance liquid chromatographic separation on a reversed-phase column. The limit of quantitation is ca. 1 pmol (1.03 pmol=lng of trospium chloride) per millilitre of plasma.
        
Related information
Citations formats
Schladitz-Keil G, Spahn H, Mutschler E (1985) Fluorimetric determination of the quaternary compound trospium and its metabolite in biological material after derivatization with benoxaprofen chloride Journal of Chromatography345: 99-110
Schladitz-Keil G, Spahn H, Mutschler E (1985) Journal of Chromatography345: 99-110