Title: Preparation, characterization and bioactivities of selenized polysaccharides from Lonicera caerulea L. fruits Shao C, Zhong J, Liu J, Yang Y, Li M, YangYu, Xu Y, Wang L Ref: Int J Biol Macromol, :, 2022 : PubMed
Native polysaccharide was obtained from Lonicera caerulea L. fruits (PLP). Two selenized polysaccharides (PSLP-1 and PSLP-2) were synthesized by the microwave-assisted HNO(3)-Na(2)SeO(3) method, where the selenium (Se) contents were 228 +/-24 and 353 +/- 36 microg/g, respectively. The molecular weights of PLP, PSLP-1, and PSLP-2 were 5.9 10(4), 5.6 10(4), and 5.1 10(4) kDa, respectively. PSLP-1 and PSLP-2 contained the same type of monosaccharides as PLP but with different molar ratios. The main chain structure of the native polysaccharide was not changed after selenization. PLP, PSLP-1, and PSLP-2 contained the same six types of glycosidic bonds. Bioactivity assays revealed that the two selenized polysaccharides possessed better antioxidant activities than PLP, but their bile acid-binding abilities and inhibitory activities on acetylcholinesterase (AChE) had weakened. In summary, PLP, PSLP-1, and PSLP-2 may be promising Se supplements in functional foods and inhibitors for the treatment of AChE.
        
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Shao C, Zhong J, Liu J, Yang Y, Li M, YangYu, Xu Y, Wang L (2022) Preparation, characterization and bioactivities of selenized polysaccharides from Lonicera caerulea L. fruits Int J Biol Macromol
Shao C, Zhong J, Liu J, Yang Y, Li M, YangYu, Xu Y, Wang L (2022) Int J Biol Macromol