The alternative splicing of neurexins (NRXs) and neuroligins (NLs) has been implicated in specifying synaptic connections. In this issue of Neuron, Koehnke et al. took a structural approach for assessing the contribution of alternative splice isoforms for beta-NRX/NL-mediated synaptic recognition.
        
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Wei Z, Zhang M (2010) A structural approach to decipher the neurexin and neuroligin splice isoform code Neuron67: 1-2