Paper Report for: Yoon_2014_Obstet.Gynecol.Sci_57_223
Reference
Title: A meningomyelocele with normal intracranial signs on ultrasound and false-negative amniotic fluid alpha-fetoprotein and acetylcholinesterase Yoon CH, Kang SK, Jin CH, Park MS, Rho JH Ref: Obstet Gynecol Sci, 57:223, 2014 : PubMed
Neural tube defects are the major targets of prenatal diagnoses, along with Down syndrome. Prenatal diagnosis of spina bifida is possible at second trimester of gestation through alpha-fetoprotein and acetylcholinesterase biochemistry assays and ultrasound. In particular, the discovery of characteristic intracranial signs on ultrasound leads to a very high diagnosis rate. However, it is rare for spina bifida to present without intracranial signs while also showing normal values of maternal serum alpha-fetoprotein, amniotic fluid alpha-fetoprotein, and acetylcholinesterase. In our hospital, a fetus with spina bifida was delivered at 37+5 weeks' gestation by cesarean section, and was continually followed up over 2 years to date.
        
Related information
Citations formats
Yoon CH, Kang SK, Jin CH, Park MS, Rho JH (2014) A meningomyelocele with normal intracranial signs on ultrasound and false-negative amniotic fluid alpha-fetoprotein and acetylcholinesterase Obstet Gynecol Sci57: 223-7
Yoon CH, Kang SK, Jin CH, Park MS, Rho JH (2014) Obstet Gynecol Sci57: 223-7