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Structure Report for: 4BDT

Name|Human acetylcholinesterase in complex with huprine W and fasciculin 2
Revelation date|29-May-2013
Family|ACHE: there are 538 genes in this family, 315 structure(s)
Gene_locus|human-ACHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Nachon, F., Carletti, E., Ronco, C., Trovaslet, M., Nicolet, Y., Jean, L., Renard, P.-Y.
Ligand|Inhibitor: Fasciculin2 Ligand in structure: Ligplot Inhibitor: HuprineW Ligand in structure: Ligplot


Reference

    Title: Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase
    Nachon F, Carletti E, Ronco C, Trovaslet M, Nicolet Y, Jean L, Renard PY
    Ref: Biochemical Journal, 453:393, 2013 : PubMed

            



Representative scheme of ACHE structure and an image from PDBsum server



Databases

PDB-Sum4BDT Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4BDT Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4BDT Structural Classification Of Protein - SCOP server
PROTEOPEDIA4bdt 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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