4N8E

Name : DPP4 complexed with compound 12a

Revelation date : 12-Feb-2014

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Ostermann, N., Zink, F., Kroemer, M.

Ligand :

References (1)

Title : Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV - Namoto_2014_Bioorg.Med.Chem.Lett_24_731
Author(s) : Namoto K , Sirockin F , Ostermann N , Gessier F , Flohr S , Sedrani R , Gerhartz B , Trappe J , Hassiepen U , Duttaroy A , Ferreira S , Sutton JM , Clark DE , Fenton G , Beswick M , Baeschlin DK
Ref : Bioorganic & Medicinal Chemistry Lett , 24 :731 , 2014
Abstract : Namoto_2014_Bioorg.Med.Chem.Lett_24_731
ESTHER : Namoto_2014_Bioorg.Med.Chem.Lett_24_731
PubMedSearch : Namoto_2014_Bioorg.Med.Chem.Lett_24_731
PubMedID: 24439847
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

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