Name : Structure of the human Wnt deacylase Notum in complex with a benzotriazole fragment JV5
Revelation date : 08-May-2019
Family : Pectinacetylesterase-Notum
Gene_locus : human-NOTUM
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Atkinson, B.N., Steadman, D., Zhao, Y., Sipthorp, J., Vecchia, L., Ruza, R.R., Jegnathan, F., Lines, G., Frew, S., Monaghan, A., Kjaer, S., Bictash, M., Jones, Y., Fish, P.V.
Ligand :
Title : Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen - Atkinson_2019_Medchemcomm_10_1361 |
Author(s) : Atkinson BN , Steadman D , Zhao YG , Sipthorp J , Vecchia L , Ruza RR , Jeganathan F , Lines G , Frew S , Monaghan A , Kjaer S , Bictash M , Jones Y , Fish PV , Zhao Y , Jones EY |
Ref : Medchemcomm , 10 :1361 , 2019 |
Abstract : Atkinson_2019_Medchemcomm_10_1361 |
ESTHER : Atkinson_2019_Medchemcomm_10_1361 |
PubMedSearch : Atkinson_2019_Medchemcomm_10_1361 |
PubMedID: 31534655 |
Gene_locus related to this paper: human-NOTUM |