7Q1O
Name : Crystal structure of human butyrylcholinesterase in complex with N-[(2S)-3-[(cyclohexylmethyl)amino]-2-hydroxypropyl]-3,3-diphenylpropanamide
Revelation date : 16-Nov-2022
Family : BCHE
Gene_locus : human-BCHE
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Brazzolotto, X.,Panek, D.,Pasieka, A.,Malawska, B.,Nachon, F.
Ligand :
References (1)
| Title : Discovery of new, highly potent and selective inhibitors of BuChE - Design, synthesis, in vitro and in vivo evaluation and crystallography studies - Panek_2023_Eur.J.Med.Chem_249_115135 |
| Author(s) : Panek D , Pasieka A , Latacz G , Zareba P , Szczech M , Godyn J , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Walczak M , Smolik M , Salat K , Hofner G , Wanner K , Wieckowska A , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 249 :115135 , 2023 |
| Abstract : Panek_2023_Eur.J.Med.Chem_249_115135 |
| ESTHER : Panek_2023_Eur.J.Med.Chem_249_115135 |
| PubMedSearch : Panek_2023_Eur.J.Med.Chem_249_115135 |
| PubMedID: 36696766 |
| Gene_locus related to this paper: human-BCHE |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
