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Structure Report for: 8AEN

Name|Human acetylcholinesterase in complex with zinc and N,N,N-trimethyl-2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazineyl)ethan-1-aminium
Revelation date|21-Jun-2023
Family|ACHE: there are 546 genes in this family, 315 structure(s)
Gene_locus|human-ACHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Nachon, F.,Dias, J.,Brazzolotto, X.
Ligand|Inhibitor: 8AM1-5a Ligand in structure: Ligplot


Reference

    Title: Grid-type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions
    Nachon F, Brazzolotto X, Dias J, Courageux C, Drozdz W, Cao XY, Stefankiewicz AR, Lehn JM
    Ref: Chembiochem, 23:e202200456, 2022 : PubMed

            



Representative scheme of ACHE structure and an image from PDBsum server



Databases

PDB-Sum8AEN Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP8AEN Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP8AEN Structural Classification Of Protein - SCOP server
PROTEOPEDIA8aen 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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