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Structure Report for: 8AM2

Name|Human butyrylcholinesterase in complex with 2,2'-(((1E,1'E)-(2-phenylpyrimidine-4,6-diyl)bis(methaneylylidene))bis(hydrazin-1-yl-2-ylidene))bis(N,N,N-trimethyl-2-oxoethan-1-aminium)
Revelation date|14-Jun-2023
Family|BCHE: there are 125 genes in this family, 91 structure(s)
Gene_locus|human-BCHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Nachon, F.,Brazzolotto, X.,Dias, J.
Ligand|Inhibitor: 8AM2-N0C Ligand in structure: Ligplot


Reference

    Title: Grid-type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions
    Nachon F, Brazzolotto X, Dias J, Courageux C, Drozdz W, Cao XY, Stefankiewicz AR, Lehn JM
    Ref: Chembiochem, 23:e202200456, 2022 : PubMed

            



Representative scheme of BCHE structure and an image from PDBsum server



Databases

PDB-Sum8AM2 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP8AM2 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP8AM2 Structural Classification Of Protein - SCOP server
PROTEOPEDIA8am2 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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