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Structure Report for: 1MX1

NameCrystal Structure of Human Liver Carboxylesterase in complex with tacrine
Revelation date22-Apr-2003
FamilyCarb_B_Chordata: there are 543 genes in this family, 20 structure(s)
Gene_locushuman-CES1
PDB FileESTHER: header of PDB entry RCSB: Full entry
Comment
Reference
    Title: Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition
    Bencharit S, Morton CL, Hyatt JL, Kuhn P, Danks MK, Potter PM, Redinbo MR
    Ref: Chemical Biology, 10:341, 2003 : PubMed

            

LigandInhibitor: Tacrine Ligand in structure: Ligplot
Representative scheme of Carb_B_Chordata structure and an image from PDBsum server
Databases
PDB-Sum1MX1 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP1MX1 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP1MX1 Structural Classification Of Protein - SCOP server
PROTEOPEDIA1mx1 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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