2ONC

Name : Crystal structure of human DPP-4 with inhibitor Alogliptin

Revelation date : 04-Mar-2008

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Feng, J., Zhang, Z., Wallace, M.B., Stafford, J.A., Kaldor, S.W., Kassel, D.B., Navre, M., Shi, L., Skene, R.J., Asakawa, T., Takeuchi, K., Xu, R., Webb, D.R., Gwaltney, S.L.

Ligand :

References (1)

Title : Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV - Feng_2007_J.Med.Chem_50_2297
Author(s) : Feng J , Zhang Z , Wallace MB , Stafford JA , Kaldor SW , Kassel DB , Navre M , Shi L , Skene RJ , Asakawa T , Takeuchi K , Xu R , Webb DR , Gwaltney SL, 2nd
Ref : Journal of Medicinal Chemistry , 50 :2297 , 2007
Abstract : Feng_2007_J.Med.Chem_50_2297
ESTHER : Feng_2007_J.Med.Chem_50_2297
PubMedSearch : Feng_2007_J.Med.Chem_50_2297
PubMedID: 17441705
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

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