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Structure Report for: 2WU4

Name|Crystal structure of mouse acetylcholinesterase in complex with fenamiphos and ortho-7
Revelation date|20-Oct-2009
Family|ACHE: there are 538 genes in this family, 315 structure(s)
Gene_locus|mouse-ACHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Hornberg, A., Artursson, E., Warme, R., Pang, Y.-P., Ekstrom, F.
Ligand|Inhibitor: Fenamiphos Ligand in structure: Ligplot Reactivator: Ortho-7 Ligand in structure: Ligplot


Reference

    Title: Crystal structures of oxime-bound fenamiphos-acetylcholinesterases: reactivation involving flipping of the His447 ring to form a reactive Glu334-His447-oxime triad
    Hornberg A, Artursson E, Warme R, Pang YP, Ekstrom F
    Ref: Biochemical Pharmacology, 79:507, 2010 : PubMed

            



Representative scheme of ACHE structure and an image from PDBsum server



Databases

PDB-Sum2WU4 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2WU4 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2WU4 Structural Classification Of Protein - SCOP server
PROTEOPEDIA2wu4 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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