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Structure Report for: 3K9B

NameCrystal Structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Cyclosarin (GF)
Revelation date19-Jan-2010
FamilyCarb_B_Chordata: there are 543 genes in this family, 20 structure(s)
Gene_locushuman-CES1
PDB FileESTHER: header of PDB entry RCSB: Full entry
CommentHemmert, A.C., Otto, T.C., Weirdl, M., Potter, P.M., Cerasoli, D.M., Redinbo, M.R.
Reference
    Title: Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin
    Hemmert AC, Otto TC, Wierdl M, Edwards CC, Fleming CD, MacDonald M, Cashman JR, Potter PM, Cerasoli DM, Redinbo MR
    Ref: Molecular Pharmacology, 77:508, 2010 : PubMed

            

LigandInhibitor: Cyclosarin Ligand in structure: Ligplot
Representative scheme of Carb_B_Chordata structure and an image from PDBsum server
Databases
PDB-Sum3K9B Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP3K9B Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP3K9B Structural Classification Of Protein - SCOP server
PROTEOPEDIA3k9b 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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