3K9B

Name : Crystal Structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Cyclosarin (GF)

Revelation date : 19-Jan-2010

Family : Carb_B_Chordata

Gene_locus : human-CES1

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Hemmert, A.C., Otto, T.C., Weirdl, M., Potter, P.M., Cerasoli, D.M., Redinbo, M.R.

Ligand :

References (1)

Title : Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin - Hemmert_2010_Mol.Pharmacol_77_508
Author(s) : Hemmert AC , Otto TC , Wierdl M , Edwards CC , Fleming CD , MacDonald M , Cashman JR , Potter PM , Cerasoli DM , Redinbo MR
Ref : Molecular Pharmacology , 77 :508 , 2010
Abstract : Hemmert_2010_Mol.Pharmacol_77_508
ESTHER : Hemmert_2010_Mol.Pharmacol_77_508
PubMedSearch : Hemmert_2010_Mol.Pharmacol_77_508
PubMedID: 20051531
Gene_locus related to this paper: human-CES1

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

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