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Structure Report for: 3KOO

Name|Crystal Structure of soluble epoxide Hydrolase with inhibitor 24D
Revelation date|28-Apr-2010
Family|Epoxide_hydrolase: there are 1154 genes in this family, 155 structure(s)
Gene_locus|human-EPHX2
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Farrow, N.A.
Ligand|Inhibitor: 24D Ligand in structure: Ligplot


Reference

    Title: Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase
    Eldrup AB, Soleymanzadeh F, Taylor SJ, Muegge I, Farrow NA, Joseph D, McKellop K, Man CC, Kukulka A, De Lombaert S
    Ref: Journal of Medicinal Chemistry, 52:5880, 2009 : PubMed

            



Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

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Databases

PDB-Sum3KOO Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP3KOO Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP3KOO Structural Classification Of Protein - SCOP server
PROTEOPEDIA3koo 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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