3KWF
Name : human DPP-IV with carmegliptin (S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-3-yl)-4-fluoromethyl-pyrrolidin-2-one
Revelation date : 12-Jan-2010
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Hennig, M., Stihle, M., Thoma, R.
Ligand :
References (1)
| Title : Discovery of carmegliptin: a potent and long-acting dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Mattei_2010_Bioorg.Med.Chem.Lett_20_1109 |
| Author(s) : Mattei P , Boehringer M , Di Giorgio P , Fischer H , Hennig M , Huwyler J , Kocer B , Kuhn B , Loeffler BM , Macdonald A , Narquizian R , Rauber E , Sebokova E , Sprecher U |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1109 , 2010 |
| Abstract : Mattei_2010_Bioorg.Med.Chem.Lett_20_1109 |
| ESTHER : Mattei_2010_Bioorg.Med.Chem.Lett_20_1109 |
| PubMedSearch : Mattei_2010_Bioorg.Med.Chem.Lett_20_1109 |
| PubMedID: 20031405 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
