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Structure Report for: 3OTQ

Name|Soluble Epoxide Hydrolase in complex with pyrazole antagonist
Revelation date|27-Oct-2010
Family|Epoxide_hydrolase: there are 1154 genes in this family, 155 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Farrow, N.A.
Ligand|Inhibitor: CHEMBL1234565 Ligand in structure: Ligplot


    Title: Substituted pyrazoles as novel sEH antagonist: investigation of key binding interactions within the catalytic domain
    Lo HY, Man CC, Fleck RW, Farrow NA, Ingraham RH, Kukulka A, Proudfoot JR, Betageri R, Kirrane T and Lombaert SD <4 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 20:6379, 2010 : PubMed


Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

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PDB-Sum3OTQ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP3OTQ Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP3OTQ Structural Classification Of Protein - SCOP server
PROTEOPEDIA3otq 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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