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Structure Report for: 3TJM

Name|Crystal Structure of the Human Fatty Acid Synthase Thioesterase Domain with an Activate Site-Specific Polyunsaturated Fatty Acyl Adduct
Revelation date|05-Oct-2011
Family|Thioesterase: there are 630 genes in this family, 73 structure(s)
Gene_locus|human-FASN
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Zhang, W., Zheng, F., Florante, A.Q.
Ligand|Inhibitor: Methyl-gamma-linolenyl-fluorophosphonate Ligand in structure: Ligplot


Reference

    Title: Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid
    Zhang W, Chakravarty B, Zheng F, Gu Z, Wu H, Mao J, Wakil SJ, Quiocho FA
    Ref: Proc Natl Acad Sci U S A, 108:15757, 2011 : PubMed

            



Representative scheme of Thioesterase structure and an image from PDBsum server

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Databases

PDB-Sum3TJM Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP3TJM Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP3TJM Structural Classification Of Protein - SCOP server
PROTEOPEDIA3tjm 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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