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Structure Report for: 4BCD

Name|Prolyl Oligopeptidase from porcine brain with a non-covalently bound P2- substituted N-acyl-prolylpyrrolidine inhibitor 3
Revelation date|13-Mar-2013
Family|S9N_PPCE_Peptidase_S9: there are 142 genes in this family, 66 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Van Der Veken, P., Fulop, V., Rea, D., Gerard, M., VanElzen, R., Joossens, J., Cheng, J.D., Baekelandt, V., DeMeester, I., Lambeir, A.M., Augustyns, K.
Ligand|Inhibitor: N-acyl-prolylpyrrolidine-inhibitor-3 Ligand in structure: Ligplot


    Title: P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy
    Van der Veken P, Fulop V, Rea D, Gerard M, Van Elzen R, Joossens J, Cheng JD, Baekelandt V, De Meester I and Augustyns K <1 more author(s)>
    Ref: Journal of Medicinal Chemistry, 55:9856, 2012 : PubMed


Representative scheme of S9N_PPCE_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum4BCD Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4BCD Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4BCD Structural Classification Of Protein - SCOP server
PROTEOPEDIA4bcd 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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