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Structure Report for: 4CIB

Name|Crystal structure of cathepsin A, , complexed with 2-(cyclohexylmethyl)propanedioic-acid compound 2
Revelation date|26-Feb-2014
Family|Carboxypeptidase_S10: there are 615 genes in this family, 20 structure(s)
Gene_locus|human-CTSA
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Schreuder, H.A., Liesum, A., Kroll, K., Boehnisch, B., Buning, C., Ruf, S., Buning, C., Sadowski, T.
Ligand|Inhibitor: 2-(cyclohexylmethyl)propanedioic-acid Ligand in structure: Ligplot


Reference

    Title: Crystal structure of cathepsin A, a novel target for the treatment of cardiovascular diseases
    Schreuder HA, Liesum A, Kroll K, Bohnisch B, Buning C, Ruf S, Sadowski T
    Ref: Biochemical & Biophysical Research Communications, 445:451, 2014 : PubMed

            



Representative scheme of Carboxypeptidase_S10 structure and an image from PDBsum server



Databases

PDB-Sum4CIB Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4CIB Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4CIB Structural Classification Of Protein - SCOP server
PROTEOPEDIA4cib 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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