Structure

Tree Display

AceDB Schema

XML Display

Feedback

Structure Report for: 4IO0

Name|Crystal structure of F128A mutant of an epoxide hydrolase from Bacillus megaterium complexed with its product (R)-3-[1]naphthyloxy-propane-1,2-diol
Revelation date|12-Feb-2014
Family|Epoxide_hydrolase: there are 1154 genes in this family, 155 structure(s)
Gene_locus|bacme-g9bex6
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Kong, X.D., Zhou, J.H., Xu, J.H. (4G02 was withdrawn and replaced by 4IO0)
Ligand|Substrate: Glycidyl-1-naphthyl-ether Ligand in structure: Ligplot Inhibitor: (R)-3-[1]naphthyloxy-propane-1,2-diol Ligand in structure: Ligplot


Reference

    Title: Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates
    Kong XD, Yuan S, Li L, Chen S, Xu JH, Zhou J
    Ref: Proc Natl Acad Sci U S A, 111:15717, 2014 : PubMed

            



Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

no Image


Databases

PDB-Sum4IO0 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4IO0 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4IO0 Structural Classification Of Protein - SCOP server
PROTEOPEDIA4io0 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer